Sodium cyanoborohydride  (NaBH3CN)
CASRN: 25895-60-7
Synonyms: Sodium cyanotrihydroborate; SCBH
Chemical formula: NaBH3CN
Mol mass: 62.84

Specification

Appearance: White or slightly yellowish powder

Purity:  96.0 % min

Melting point: ≥ 242°C with decomposition

Also available:
NaBH3CN in NaOH solution

Packaging
1kg per plastic bottle in outer metal container.
Sample quantities are available.
Physical properties

Odorless white or slightly yellowish powder

Ignition temperature: 175°C

Solubility in water: 2120 g/l at 29°C

Readily soluble in methanol; slightly soluble in ethanol; non-soluble in diethyl ether, benzene, & hexane

Environmental, Health & Safety
Sodium cyanoborohydride is a hazardous material that must be shipped, stored, handled, used, and disposed by qualified individuals according to the law & instructions provided on the MSDS (available from Boron Specialties).

Country of origin: United States.
APPLICATIONS
Organic synthesis

Highly selective reducing agent for aldehydes, ketones, oximes, enamines. Especially useful for reductive amination of ketones and aldehydes, reductive alkylation of amines and hydrazines, reductive displacement of halides & tosylates, and deoxygenation of aldehydes & ketones.


Reductive methylation of protein amino groups (Sanders et al, Biochem. J. (1982) 203, 331-334)


Synthesis of primary amines from aldehydes via reductive amination sans protecting groups.  (Dangerfield et al, J. Org. Chem., 2010, 75, 5470-5477)
Borch et al, “The Cyanohydridoborate Anion as a Selective Reducing Agent,” JACS, 93:12, 1971.